Old Trafford has borne witness to some memorable matches between Arsenal and Manchester United over the years, and now Arsene Wenger will be travelling to the hallowed turf for the last time ever as Gunners manager on Sunday.
The 68-year-old has had a number of unsavoury spats with Mourinho since the Portuguese took over at Chelsea in 2004 - with the rivalry between the pair often leading to verbal - and sometimes physical - altercations.
There was a highly-charged atmosphere for Wenger's penultimate home game in charge and the hosts were given plenty of encouragement early on, even when still up against Atletico's full complement.
Arsenal and Manchester United will lock their horns on Sunday.
So Mourinho may have to settle for a friendly goodbye for now, although Wenger also warned that his old rival may not have seen the last of him. They were excellent in beating Tottenham Hotspur at Wembley Stadium in the FA Cup semi-final in their most recent outing and are on course to secure second place in the table.
However, he might not be ready to accept Mourinho's offer of a attractive friendship just yet. He urged Mourinho not push him into creating a scene. I want to go peacefully, with Mourinho as well because he is a great manager. I must say as well it is very hard when you play against fellow managers, they get reported things that you have not necessarily said.
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Obviously, this is Arsene Wenger's last trip to his great adversaries.
Former Manchester United chairman Martin Edwards revealed in his 2017 autobiography that he held talks with Wenger over replacing Ferguson at Old Trafford when the Scot originally announced he would retire in 2002. "Now it's peaceful. Both of us have calmed down and with time respect takes over", Wenger said. The Gunners entered the crunch clash nine points behind Sir Alex Ferguson's men, knowing full well that only a victory would keep their slight hopes of a domestic double alive.
It will be the first time Sanchez will face off against his former side and Wenger has opened up about what it will feel like to see him line up in the red of Manchester United instead of Arsenal.
"I speak to everybody".
With what Wenger had achieved between 1996 and 2005, and what he had done for the club during this time, he was always going to be given the chance to exit on his own terms.